Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report

Objective: Nasal extranodal NK/T-cell lymphoma is a rare aggressive lesion, characterized by a destructive process of the upper respiratory tract that has an unusual and rapid evolution. Diagnosis is often difficult and requires expert clinical examination and analysis of biopsies using immunohistochemistry. Case report: 34 years-old man with no relevant medical history, presented with an asymptomatic necrotizing lesion on palate and nasal obstruction. Two biopsies were performed with no conclusive results. By the third time, atypical lymphoid tissue was found surrounded by intense necrosis. The diagnosis was conf irmed by immunohistochemistry. Chemotherapy was the treatment of choice follow by radiotherapy. The patient presented satisfactory evolution but one year after treatment a recidive was detected and patient died 5 months later from lung metastasis. Conclusion:Suspicious ulcerative lesions in the midline head and neck region must have extranodal NK/T-cell lymphoma as differential diagnosis and repeated biopsies should be taken to confirm diagnosis.